class='kwd-title'>Keywords: fermentation, genoto'/> Acute toxicity and genotoxicity of fermented traditional medicine oyaksungi-san
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Acute toxicity and genotoxicity of fermented traditional medicine oyaksungi-san

机译:发酵传统药物御茶山的急性毒性和遗传毒性

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摘要

class="kwd-title">Keywords: fermentation, genotoxicity, oyaksungi-san, traditional medicine, toxicity class="head no_bottom_margin" id="abs0010title">AbstractBackgroundThe traditional medicine oyaksungi-san (OY) has been prescribed in East Asia for hundreds of years for the treatment of stroke, paralysis, and ataxia. OY also has therapeutic effects on arthralgia, myalgia, and rheumatoid arthritis, and recent studies have shown its protective effects against apoptosis of hippocampal cells and its anti-inflammatory effects on the peripheral blood cells of patient with cerebral infarction. Many studies have explored the use of traditional medicine and herb materials in the development of safe, novel, and effective pharmaceuticals with fewer side effects. These efforts commonly adopt a bioconversion tool for fermentation with beneficial microbes. However, only pharmaceuticals with high levels of safety and low levels of toxicity can be used in healthcare system.
机译:<!-fig ft0-> <!-fig @ position =“ anchor” mode =文章f4-> <!-fig mode =“ anchred” f5-> <!-fig / graphic | fig / alternatives / graphic mode =“ anchored” m1-> class =“ kwd-title”>关键字:发酵,遗传毒性,oyaksungi-san,传统药物,毒性 class =“ head no_bottom_margin” id =“ abs0010title”>摘要背景东亚已经开出了数百年的传统药物oyaksungi-san(OY),用于治疗中风,瘫痪和共济失调。 OY还对关节痛,肌痛和类风湿性关节炎具有治疗作用,最近的研究表明其对海马细胞凋亡的保护作用以及对脑梗死患者外周血细胞的抗炎作用。许多研究已经探索了在开发安全,新颖,有效且副作用较少的药物中使用传统药物和草药的方法。这些努力通常采用生物转化工具与有益微生物发酵。但是,只有具有高安全性和低毒性的药物才能用于医疗保健系统。

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