Orally Formulated Artemisinin in Healthy Fasting Vietnamese Male Subjects: A Randomized Four-Sequence Open-Label Pharmacokinetic Crossover Study

摘要

BackgroundArtemisinin derivatives are used in antimalarial drug combination therapy. Artemisinin and piperaquine have recently been proven to be prospective candidates for combination therapy in the treatment of uncomplicated Plasmodium falciparum malaria.