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Critical Appraisal of Programmed Death Ligand 1 Reflex Diagnostic Testing: Current Standards and Future Opportunities

机译：程序性死亡配体1反射诊断测试的严格评估：当前的标准和未来的机会

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IntroductionPatient suitability to anti–programmed death ligand 1 (PD-L1) immune checkpoint inhibition is key to the treatment of NSCLC. We present, applied to PD-L1 testing: a comprehensive cross-validation of two immunohistochemistry (IHC) clones; our descriptive experience in diagnostic reflex testing; the concordance of IHC to in situ RNA (RNA-ISH); and application of digital pathology.

机译：简介患者对抗编程死亡配体1（PD-L1）免疫检查点抑制的适应性是治疗NSCLC的关键。目前，我们将其应用于PD-L1测试：两个免疫组织化学（IHC）克隆的全面交叉验证；我们在反射诊断测试中的描述性经验； IHC与原位RNA的一致性（RNA-ISH）；和数字病理学的应用。

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期刊名称 Elsevier Sponsored Documents
作者
Matthew P. Humphries; Stephen McQuaid; Stephanie G. Craig; Victoria Bingham; Perry Maxwell; Manisha Maurya; Fiona McLean; James Sampson; Patricia Higgins; Christine Greene; Jacqueline James; Manuel Salto-Tellez;
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年(卷),期 -1(14),1
年度 -1
页码 45–53
总页数 9
原文格式 PDF
正文语种
中图分类
关键词
Validation Programmed death ligand 1 Clinical workflow RNAscope Image analysis;

机译：验证;程序性死亡配体1;临床工作流程;RNAscope;图像分析;
入库时间 2022-08-21 10:59:25

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1. Critical Appraisal of Programmed Death Ligand 1 Reflex Diagnostic Testing: Current Standards and Future Opportunities [J] . Humphries Matthew P., McQuaid Stephen, Craig Stephanie G., Journal of thoracic oncology: official publication of the International Association for the Study of Lung Cancer . 2019,第1期

机译：编程死亡配体1反射诊断测试的关键评估：当前标准和未来机会
2. Current and future drug combination strategies based on programmed death-1/programmed death-ligand 1 inhibitors in non-small cell lung cancer [J] . Ying Cheng, Hui Li, Liang Zhang, 中华医学杂志（英文版） . 2021,第015期

机译：基于编程死亡-1 /编程死亡 - 配体1抑制剂的当前和未来的药物组合策略在非小细胞肺癌中
3. General principles of diagnostic testing as related to painful lumbar spine disorders: a critical appraisal of current diagnostic techniques. [J] . Saal JS Spine . 2002,第22期

机译：与腰椎疼痛相关的诊断测试的一般原则：对当前诊断技术的严格评估。
4. OPPORTUNITIES FOR MICROWAVES AND PHOTONICS IN MEDICAL DIAGNOSTICS AND THERAPY, Part II - BREAST CANCER DETECTION: CURRENT LIMITATIONS AND FUTURE DIRECTION [C] . Stern L. H. International Topical Meeting on Microwave Photonics . 2003

机译：医学诊断和治疗中微波和光子学的机会，第二部分 - 乳腺癌检测：当前限制和未来方向
5. The effect of the "Watson-Glaser Critical Thinking Appraisal" test preparation program on the critical thinking of teacher education program applicants. [D] . Valdes-Corbeil, Maria Elena. 2005

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6. Evaluation of an online training tool for scoring programmed cell death ligand-1 (PD-L1) diagnostic tests for lung cancer [O] . Bharat Jasani, Gudrun Bänfer, Rebecca Fish, 2020

机译：评估在线编程工具以评估肺癌编程性细胞死亡配体1（PD-L1）诊断测试的工具
7. Is There a Role for Programmed Death Ligand-1 Testing and Immunotherapy in Colorectal Cancer With Microsatellite Instability? Part II—The Challenge of Programmed Death Ligand-1 Testing and Its Role in Microsatellite Instability-High Colorectal Cancer [O] . Esmeralda Celia Marginean, Barbara Melosky 2017

机译：是否有针对编程死亡配体-1测试和直肠癌免疫疗法的作用，具有微卫星不稳定性？第二部分 - 编程死亡配体-1测试的挑战及其在微卫星不稳定 - 高结肠癌中的作用
8. Testability/Diagnostics Encyclopedia Program (Phase 1) Testability/Diagnostics Linkages in Mil-Standards and Handbooks [R] . Neumann, G. W., Barthelenghi, G. 1988

机译：可测试性/诊断百科全书计划（第1阶段）可测性/诊断链接，包括军用标准和手册

Critical Appraisal of Programmed Death Ligand 1 Reflex Diagnostic Testing: Current Standards and Future Opportunities

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