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Tailored meta-analysis: an investigation of the correlation between the test positive rate and prevalence

机译:量身定制的荟萃分析:对测试阳性率与患病率之间相关性的调查

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摘要

Background and ObjectiveMeta-analysis may produce estimates that are unrepresentative of a test's performance in practice. Tailored meta-analysis (TMA) circumvents this by deriving an applicable region for the practice and selecting the studies compatible with the region. It requires the test positive rate, r and prevalence, p being estimated for the setting but previous studies have assumed their independence. The aim is to investigate the effects a correlation between r and p has on estimating the applicable region and how this affects TMA.
机译:背景和ObjectiveMeta分析可能会产生无法代表实际测试性能的估计。量身定制的荟萃分析(TMA)通过得出适用于该实践的区域并选择与该区域兼容的研究来规避这一问题。它要求测试阳性率,r和患病率,其中p是根据具体情况估算的,但以前的研究假设其独立性。目的是研究r和p之间的相关性对估计适用区域的影响及其对TMA的影响。

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