首页> 美国卫生研究院文献>International Journal of Hematology-Oncology and Stem Cell Research >Is It Rational to Study Coagulations Test Routinely before Operations and Invasive Procedure: Single Center Retrospective Study
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Is It Rational to Study Coagulations Test Routinely before Operations and Invasive Procedure: Single Center Retrospective Study

机译:在手术和有创手术之前定期研究凝血试验是否合理:单中心回顾性研究

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摘要

>Background: Detailed history taking, physical examination and laboratory tests are useful tools to document any abnormal bleeding risk before an operation or an invasive procedure. Although coagulation tests are routinely used to demonstrate the pathological situations at the coagulation cascade or to follow-up the anticoagulation therapies, their role in determining the bleeding risk in preoperative patients is controversial. >Materials and Methods: In this study, we aimed to evaluate the patients referring to our hematology clinic at Izmir Katip Celebi University Hospital for preoperative consultation due to elevated levels of coagulation tests. >Results: Fifty-six patients with high PT/PTT levels were enrolled in this study. Twenty-six (46.4%) patients were male and 30 (53.6%) were female. The median age was 34 (18-75) years. We documented bleeding history in 12 (21.4%) patients. The patients having a bleeding history revealed mostly abnormal uterine bleeding, epistaxis, and gingival bleeding. Life threatening bleeding was not reported in any of the patients.  The operations were cancelled or postponed at least one month in 38 (67.8%) and 10 (17.8%) patients, respectively. Per-operative or post-operative abnormal bleeding was not documented. We did not find any statistically significant difference between groups with or without elevated coagulation tests in terms of abnormal bleeding in the operations. >Conclusion: Coagulations tests should be studied in selected group of patients. Additionally, mildly elevated results should be interpreted carefully to decrease the rate of cancellation and delay in operations and unnecessary increase in costs.
机译:>背景:详细的病史记录,体格检查和实验室检查是记录手术或侵入性手术之前任何异常出血风险的有用工具。尽管常规地使用凝血试验来证明凝血级联的病理情况或随访抗凝疗法,但它们在确定术前患者出血风险中的作用尚存争议。 >材料和方法:由于凝血试验水平升高,我们的目的是评估在伊兹密尔卡提普西皮利大学医院血液科转诊的患者进行术前咨询的情况。 >结果:这项研究纳入了56例PT / PTT高水平的患者。男性为26位(46.4%),女性为30位(53.6%)。中位年龄为34(18-75)岁。我们记录了12名(21.4%)患者的出血史。有出血史的患者大多数表现为异常子宫出血,鼻epi和牙龈出血。在所有患者中均未报告有威胁生命的出血。分别对38例(67.8%)和10例(17.8%)的患者取消或推迟了至少一个月的手术。没有记录术中或术后异常出血。在手术中异常出血方面,有或没有凝血试验升高的组之间,我们没有发现统计学上的显着差异。 >结论:应在选定的患者组中进行凝血试验。此外,应谨慎解释轻微升高的结果,以减少取消率和操作延迟,并不必要地增加成本。

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