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Patient-tailored Drug-eluting Stent Choice – A Solution for Patients with Diabetes

机译:量身定制的药物洗脱支架选择–糖尿病患者的解决方案

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摘要

Although second-generation drug-eluting stents (DES) have improved outcomes in percutaneous coronary interventions (PCIs), important unmet needs remain. Two symposia at EuroPCR 2015 focused on two challenging scenarios. First, patients with diabetes mellitus (DM) have generally inferior outcomes following PCI. The Cre8™ stent (manufactured by CID Spa, member of Alvimedica Group) has shown unique efficacy in subpopulations of patients with DM during clinical trials. A live case in a patient with diabetes illustrated the challenges of complex multivessel disease. Second, optimising stent selection towards devices that have demonstrated complete and early endothelialisation offers the potential to reduce the duration of dual antiplatelet therapy. The Cre8™ DES features a polymer-free platform and has been associated with low rates of in-stent thrombosis.
机译:尽管第二代药物洗脱支架(DES)在经皮冠状动脉介入治疗(PCI)中的效果有所改善,但仍存在重要的未满足需求。 2015年欧洲PCR的两个专题讨论会重点讨论了两个具有挑战性的方案。首先,患有糖尿病(DM)的患者一般在PCI后效果较差。 Cre8™支架(由Alvimedica Group的成员CID Spa生产)在临床试验中对DM患者亚群显示出独特的功效。糖尿病患者的活病例说明了复杂的多支血管疾病的挑战。其次,针对已证明已完全和早期内皮化的装置优化支架选择,有可能减少双重抗血小板治疗的持续时间。 Cre8™DES具有无聚合物平台,并且支架内血栓形成率低。

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