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Microcurrent skin patches for postoperative pain control in total knee arthroplasty: a pilot study

机译:微电流皮肤贴片在全膝关节置换术中控制术后疼痛

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摘要

Pain control following painful orthopaedic procedures such as total knee arthroplasty (TKA) is an ongoing challenge, as current pain management techniques often result in under-medication and/or complications. In a study designed to test the effect of the micro-current skin patch (MCT) on pain relief in patients following TKA, we followed 24 patients, randomly divided into two groups, one group receiving MCT plus tramadol hydrochloride (tramadol) for pain relief and a control group receiving only tramadol, for 10 days postoperatively. Tramadol was given intramuscularly in increment doses of 100 mg, as needed, for the duration of the study period. Pain was assessed daily using a visual analogue score (VAS). Other parameters, including the effect of MCT on the dose of tramadol needed for pain relief, the degree of wound healing measured at the end of the follow-up period, category of the wound 10 days postoperatively (1, 2 or 3) and total drain fluid volume, were also assessed. During the 10-day postoperative period there was a progressive decrease in pain in patients of both groups, however the patients of the MCT group showed a consistently lower VAS throughout the observation period, most markedly on those follow-up days with the highest pain scores in patients of the control group. This effect was monitored on the basis of the average dose of tramadol administered per day: 200.0±7.0 mg/day in the control group and 63.3±15.8 mg/day in the MCT group. Wound healing was better with the application of the MCT patch: grade 1 wounds were observed in 50% of the patients of the MCT group as compared to 8.3% in control group. The total drain volume was lower in patients of the MCT group compared to the controls (1020.8±211.6 and 1170.8±243.5 ml, respectively). None of the patients indicated that they wished to discontinue MCT therapy. This pilot study shows that MCT therapy led to better pain control with a markedly lower need for tramadol as compared to the control group. This better pain control was accompanied by a better healing of the wound and a lower drain volume.
机译:疼痛的整形外科手术(例如全膝关节置换术(TKA))后的疼痛控制是一个持续的挑战,因为当前的疼痛管理技术通常会导致用药不足和/或并发症。在一项旨在测试微电流皮肤贴剂(MCT)对TKA术后患者的疼痛缓解效果的研究中,我们追踪了24位患者,随机分为两组,一组接受MCT加盐酸曲马多(tramadol)缓解疼痛对照组仅接受术后10天的曲马多治疗。在研究期间,视需要肌注曲马多,剂量为100 mg。每天使用视觉模拟评分(VAS)评估疼痛。其他参数,包括MCT对缓解疼痛所需的曲马多剂量的影响,在随访期结束时测量的伤口愈合程度,术后10天(1、2或3)的伤口类别和总排出的液体量也进行了评估。术后10天,两组患者的疼痛逐渐减轻,但是MCT组的患者在整个观察期内表现出持续降低的VAS,最明显的是在那些疼痛评分最高的随访日对照组患者。根据每天服用曲马多的平均剂量监测这种效果:对照组为200.0±7.0 mg /天,MCT组为63.3±15.8 mg /天。使用MCT贴片可更好地治愈伤口:MCT组50%的患者观察到1级伤口,而对照组为8.3%。与对照组相比,MCT组患者的总引流量更低(分别为1020.8±211.6和1170.8±243.5 ml)。没有患者表示希望停止MCT治疗。这项初步研究表明,与对照组相比,MCT治疗可更好地控制疼痛,对曲马多的需求明显降低。这种更好的疼痛控制伴随着伤口的更好愈合和更低的引流量。

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