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The Occurrence of N-nitrosodimethylamine (NDMA) in Swimming Pools: An Overview

机译:在游泳池中的N-硝基甲酰亚甲胺(NDMA)发生:概述

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摘要

The occurrence of several disinfectant byproducts has been investigated in swimming pools. Until now, there are only a few studies on nitrosamine, particularly N-nitrosodimethylamine in swimming pool water. This could be due to the lack of a suitable method that is sensitive enough for the measurement of N-nitrosodimethylamine in pool waters. Other disinfectant byproducts formed in pool water widely documented are trihalomethanes, haloacetic acids, halonitromethanes, and chloramines but inadequate information on N-nitrosodimethylamine. This paper provides a review of the nitrogenous disinfectant byproduct in swimming pools and its health implications. Anthropogenic substances introduced by swimmers such as sweat, lotions, and urine contribute to the formation of N-nitrosodimethylamine. The reaction of secondary amines such as dimethylamine with mono/dichloroamines produced dimethyl hydrazine and further undergo oxidation to form N-nitrosodimethylamine. The reaction of chlorine and other disinfectants with these anthropogenic sources in swimming pools cause cancer and asthma in human tissues. Thus, the assessment of N-nitrosodimethylamine in the swimming pool is less well documented. Therefore, the health consequences, mutagenic, and genotoxic potentials of N-nitrosodimethylamine should be the focus of more research studies.
机译:在游泳池中调查了几种消毒剂副产品的发生。到目前为止,在游泳池水中只有少数关于亚硝胺,特别是N-亚硝二甲胺酰胺的研究。这可能是由于缺乏适合敏感的方​​法,足以测量池水中的N-硝基二甲胺氨基氨基。在泳池水中形成的其他消毒剂副产物广泛记录是三卤代甲烷,卤代乙酸,卤代硝基甲烷和氯胺,但在N-亚硝二甲胺中的信息不足。本文介绍了游泳池中含氮消毒剂副产品及其健康影响。由游泳剂,乳液和尿液如汗水,乳液和尿液引入的人为物质有助于形成N-硝基甲酰亚胺。仲胺如二甲胺的反应,用单甲酰胺产生二甲基肼并进一步进行氧化以形成N-硝基甲酰亚胺。氯和其他消毒剂与游泳池中的这些人为来源的反应导致人类组织中的癌症和哮喘。因此,在游泳池中的N-硝基甲酰亚胺甲胺的评估不太清晰。因此,N-硝基甲酰胺的健康后果,致突变和遗传毒性潜力应该是更多研究研究的重点。

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