An 11-year-old girl presented with excessive and slowly progressive sweating of her palms and soles for the past 2 years. Her symptoms persist throughout the day and become minimal or absent during sleep. These symptoms are exaggerated during stress, reading, writing and whenever she is being watched. There was no excessive sweating over other body parts, such as the face, armpits and groins. Because of the excessive sweating, she has difficulty in holding a pen and doing her school homework and feels shy in front of others. There was no history of repeated skin infection, pain, pungent body odour and heat intolerance. She denied any history of drug intake. She was born to consanguineous parents, and her younger brother (8 years old) has similar complaints since 6 years of age. Her maternal grandfather also had similar symptoms since childhood (figure 1).
展开▼
