ChIP-seq data collection and pre-processing. a TFs shared by both the K562 (red) and GM12878 (blue) cell lines from ENCODE, in addition to DNase sequencing and histone modification data, are pooled together to form the set of regulatory elements used in the analysis. b Classification of the common TFs between K562 and GM12878. Specific DBD family classifications are also given. c The heatmap shows the top and bottom 20 TFs with high and low log fold change of expression between GM12878 and K562. The bar plot shows the log10 of the FPKM expression values for each of these TFs
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