Treatment outcome and long-term follow-up of central nervous system germ cell tumor using upfront chemotherapy with subsequent photon or proton radiation therapy: a single tertiary center experience of 127 patients

摘要

Overall treatment scheme and classification of patients. Upfront chemotherapy alternating between courses A and B, and a total of 4 cycles of chemotherapy (A-B-A-B) were administered. Subsequent radiation therapy was administered using photon (XRT) or proton (PRT) therapy according to the patients’ choice. †Carboplatin 450 mg/m2 was administered on day 1 until 2008, whereas the same dose of carboplatin was administered on days 1–2 from 2009