Prognostic significance of SOCS1 and SOCS3 tumor suppressors and oncogenic signaling pathway genes in hepatocellular carcinoma

摘要

Expression of SOCS1 and SOCS3 genes in the TCGA-LIHC dataset and their prognostic significance. a Expression levels of SOCS1 and SOCS3 genes in the HCC tumors compared to normal liver tissue in the TCGA dataset. b Expression levels of SOCS1 and SOCS3 in different grades of HCC specimens. c Impact of high SOCS1 and SOCS3 expression on overall patient survival. The upper high expression quartile was compared with the remaining three-quarts of low/medium expression in the Kaplan-Meier plot