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Monte Carlo simulation of 6‐MV dynamic wave VMAT deliveries by Vero4DRT linear accelerator using EGSnrc moving sources

机译:Monte Carlo仿真使用EGSNRC移动源的Vero4drt线性加速器6MV动态波VMAT交付

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摘要

The commissioning and benchmark of a Monte Carlo (MC) model of the 6‐MV Brainlab‐Mitsubishi Vero4DRT linear accelerator for the purpose of quality assurance of clinical dynamic wave arc (DWA) treatment plans is reported. Open‐source MC applications based on EGSnrc particle transport codes are used to simulate the medical linear accelerator head components. Complex radiotherapy irradiations can be simulated in a single MC run using a shared library format combined with BEAMnrc “source20.” Electron energy tuning is achieved by comparing measured vs simulated percentage depth doses (PDDs) for MLC‐defined field sizes in a water phantom. Electron spot size tuning is achieved by comparing measured and simulated inplane and crossplane beam profiles. DWA treatment plans generated from RayStation (RaySearch) treatment planning system (TPS) are simulated on voxelized (2.5 mm3) patient CT datasets. Planning target volume (PTV) and organs at risk (OAR) dose–volume histograms (DVHs) are compared to TPS‐calculated doses for clinically deliverable dynamic volumetric modulated arc therapy (VMAT) trajectories. MC simulations with an electron beam energy of 5.9 MeV and spot size FWHM of 1.9 mm had the closest agreement with measurement. DWA beam deliveries simulated on patient CT datasets results in DVH agreement with TPS‐calculated doses. PTV coverage agreed within 0.1% and OAR max doses (to 0.035 cc volume) agreed within 1 Gy. This MC model can be used as an independent dose calculation from the TPS and as a quality assurance tool for complex, dynamic radiotherapy treatment deliveries. Full patient CT treatment simulations are performed in a single Monte Carlo run in 23 min. Simulations are run in parallel using the Condor High‐Throughput Computing software1 on a cluster of eight servers. Each server has two physical processors (Intel Xeon CPU E5‐2650 0 @2.00 GHz), with 8 cores per CPU and two threads per core for 256 calculation nodes.
机译:报道了6-MV Brainlab-Mitsubishi Vero4drt线性加速器的Monte Carlo(MC)模型的调试和基准,用于质量保证临床动态波弧(DWA)治疗计划。基于EGSNRC粒子传输代码的开源MC应用程序用于模拟医用线性加速器头组件。可以使用与BeamNRC“Source20组合的共享库格式来模拟复杂的放射疗法照射。通过比较水体模型的MLC定义的场尺寸的测量VS模拟百分比深度剂量(PDD)来实现电子能调谐。通过比较测量和模拟的平面和交叉平面梁轮廓来实现电子点尺寸调谐。从射线(Raysearch)治疗计划系统(TPS)产生的DWA治疗计划在体轴(2.5 mm3)患者CT数据集上模拟。将风险(OAR)剂量直方图(DVHs)的计划靶体积(PTV)和器官与TPS计算的剂量进行比较,用于临床可输送的动态体积调制电弧疗法(VMAT)轨迹。 MC模拟具有5.9 meV的电子束能量和1.9毫米的光斑尺寸为1.9 mm,具有与测量最近的协议。患者CT数据集模拟DWA梁递送导致DVH协议与TPS计算的剂量。 PTV覆盖范围在0.1%和OAR MAX剂量内(0.035cc卷)同意,在1 GY之内商定。该MC模型可作为来自TPS的独立剂量计算,作为复杂的动态放射治疗交付的质量保证工具。全患者CT治疗模拟在23分钟内的单个蒙特卡罗进行。使用八个服务器集群上的Condor高吞吐量计算Software1并行地运行模拟。每个服务器都有两个物理处理器(Intel Xeon CPU E5-2650 0 @ 2.00 GHz),每个CPU有8个核心,每个核心为256个计算节点。

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