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Comparisons of Four Protein-Binding Models Characterizing the Pharmacokinetics of Unbound Phenytoin in Adult Patients Using Non-Linear Mixed-Effects Modeling

机译：四种蛋白质结合模型的比较表征成年患者未结合酚类药代动力学的非线性混合效应建模

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The online version of this article (10.1007/s40268-020-00323-2) contains supplementary material, which is available to authorized users.

机译：本文的在线版本（10.1007 / s40268-020-00323-2）包含辅助材料，可供授权用户使用。

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期刊名称 Drugs in RD
作者
Heajin Jun; Yan Rong; Catharina Yih; Jordan Ho; Wendy Cheng; Tony K. L. Kiang;
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作者单位

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年(卷),期 2020(20),4
年度 2020
页码 343–358
总页数 16
原文格式 PDF
正文语种
中图分类药学;
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1. Comparisons of Four Protein-Binding Models Characterizing the Pharmacokinetics of Unbound Phenytoin in Adult Patients Using Non-Linear Mixed-Effects Modeling [J] . Heajin Jun, Yan Rong, Catharina Yih, Drugs in R&D . 2020,第4期

机译：四种蛋白质结合模型的比较表征成年患者未结合酚类药代动力学的非线性混合效应建模
2. A Population Pharmacokinetic Model of Valproic Acid in Pediatric Patients with Epilepsy: A Non-Linear Pharmacokinetic Model Based on Protein-Binding Saturation [J] . Ding Junjie, Wang Yi, Lin Weiwei, Clinical pharmacokinetics . 2015,第3期

机译：小儿癫痫患者丙戊酸的群体药代动力学模型：基于蛋白质结合饱和度的非线性药代动力学模型
3. Impact of modelling intra-subject variability on tests based on non-linear mixed-effects models in cross-over pharmacokinetic trials with application to the interaction of tenofovir on atazanavir in HIV patients. [J] . Panhard X, Taburet AM, Piketti C, Statistics in medicine . 2007,第6期

机译：在交叉药代动力学试验中，基于非线性混合效应模型的受试者内部变异建模对测试的影响，以及将替诺福韦与阿扎那韦在HIV患者中的相互作用应用。
4. Pharmacokinetic simulator with three-dimensionalgraphical models: Sociotechnological interface ofpharmacokinetics for medical personnel, patients,and medicinal chemists [C] . Michihisa Koyama, Kotaro Okushi, Hideyuki Tsubo International Symposium for Interface Oral Health Science . 2005

机译：具有三维图模型的药代动力学模拟器：医科员工，患者和药物化学家的医学界面
5. Developing patient specific population pharmacokinetic models and comparing compartmental vs. non-compartmental analysis for the prediction of individual pharmacokinetic parameters. [D] . Hines, Daniel Joseph. 2009

机译：开发患者特定人群的药代动力学模型并比较隔室与非隔室分析，以预测各个药代动力学参数。
6. Non-Linear Mixed-Effects Pharmacokinetic Modeling of the Novel COX-2 Selective Inhibitor Vitacoxib in Cats [O] . Jianzhong Wang, Benjamin K. Schneider, Hongzhi Xiao, 2020

机译：非线性混合效应于猫的新型Cox-2选择性抑制剂vitacoxib的药代通知型模型
7. Comparisons of Four Protein-Binding Models Characterizing the Pharmacokinetics of Unbound Phenytoin in Adult Patients Using Non-Linear Mixed-Effects Modeling [O] . Heajin Jun, Yan Rong, Catharina Yih, 2020

机译：四种蛋白质结合模型的比较表征成年患者未结合酚类药代动力学的非线性混合效应建模

Comparisons of Four Protein-Binding Models Characterizing the Pharmacokinetics of Unbound Phenytoin in Adult Patients Using Non-Linear Mixed-Effects Modeling

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