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Fate of β-Carotene within Loaded Delivery Systems in Food: State of Knowledge

机译:食品中装载送货系统中β-胡萝卜素的命运:知识状态

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摘要

Nanotechnology has opened new opportunities for delivering bioactive agents. Their physiochemical characteristics, i.e., small size, high surface area, unique composition, biocompatibility and biodegradability, make these nanomaterials an attractive tool for β-carotene delivery. Delivering β-carotene through nanoparticles does not only improve its bioavailability/bioaccumulation in target tissues, but also lessens its sensitivity against environmental factors during processing. Regardless of these benefits, nanocarriers have some limitations, such as variations in sensory quality, modification of the food matrix, increasing costs, as well as limited consumer acceptance and regulatory challenges. This research area has rapidly evolved, with a plethora of innovative nanoengineered materials now being in use, including micelles, nano/microemulsions, liposomes, niosomes, solidlipid nanoparticles, nanostructured lipids and nanostructured carriers. These nanodelivery systems make conventional delivery systems appear archaic and promise better solubilization, protection during processing, improved shelf-life, higher bioavailability as well as controlled and targeted release. This review provides information on the state of knowledge on β-carotene nanodelivery systems adopted for developing functional foods, depicting their classifications, compositions, preparation methods, challenges, release and absorption of β-carotene in the gastrointestinal tract (GIT) and possible risks and future prospects.
机译:纳米技术开辟了提供生物活性剂的新机会。它们的生理化学特性,即小尺寸,高表面积,独特的组成,生物相容性和生物降解性,使这些纳米材料成为β-胡萝卜素递送的有吸引力的工具。通过纳米颗粒递送β-胡萝卜素不仅改善了靶组织中的生物利用度/生物累积,而且还会减少其在加工过程中对环境因素的敏感性。无论这些益处如何,纳米载波都有一些限制,例如感觉质量的变化,食物矩阵的改变,增加成本,以及有限的消费者接受和监管挑战。该研究领域已经迅速发展,目前正在使用过多的创新纳米工程材料,包括胶束,纳米/微乳液,脂质体,定位瘤,固体脂质纳米粒子,纳米结构脂质和纳米结构载体。这些纳米送货系统使传统的递送系统出现古老,并承诺在加工过程中进行更好的增溶化,保护,改善保质期,更高的生物利用度以及控制和目标释放。本综述提供了有关用于开发功能食品的β-胡萝卜素纳米碳交付系统的知识状态的信息,描绘其分类,组合物,制备方法,挑战,胃肠道(Git)和可能的风险和可能的风险和可能的风险和可能的风险前景。

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