High sensitivity troponin measurement in critical care: Flattering todeceive or ‘never means nothing’?

摘要

Troponin elevation is central to the diagnosis of acute type 1 myocardialinfarction. It is, however, elevated in a range of other conditions,including type 2 myocardial infarction, and this setting is increasinglyassociated with adverse clinical outcomes. Patients within intensive carefrequently have at least one organ failure together with a range ofco-morbidities. Interpretation of troponin assay results in this populationis challenging. This clinical uncertainty is compounded by the introductionof ever more sensitive troponin assays.