首页> 美国卫生研究院文献>Regenerative Biomaterials >Mechanical and biological properties of Ti–(0–25 wt)Nb alloys for biomedical implants application
【2h】

Mechanical and biological properties of Ti–(0–25 wt)Nb alloys for biomedical implants application

机译:用于生物医学植入物的Ti–(0–25 wt%)Nb合金的力学和生物学性能

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。

摘要

Binary titanium–niobium (Ti–Nb) alloys have recently been attracted due to low Young’s moduli and non-toxic properties. This study explores the influence of low Nb content (0–25 wt%) on the comprehensive parameters of tensile stress–strain relationships (ultimate strength (σ ), yield strength (σ ) and elastic modulus ( )), surfaces properties (Vickers microhardness, surface roughness ( ), water contact angle (WCA), X-ray diffraction (XRD) and scanning electron microscopy (SEM)), corrosion resistance (in artificial saliva and lactic acid) and biological properties (cytotoxicity and alkaline phosphatase activity of MC3T3-E1 pre-osteoblasts) of Ti– Nb alloys (  = 5, 10, 15, 20 and 25 wt%), with using commercially pure grade 2 titanium (cp-Ti) as control. XRD results shown that all the Ti– Nb alloys comprised α + β Ti alloy phases, such that the β phase increased correspondingly with the increased amount of Nb in the alloy, as well as the reduction of (69–87 GPa). Except Ti–5Nb, all other Ti– Nb alloys showed a significantly higher hardness, increased σ and σ , and decreased WCA compared with cp-Ti. No corrosion was detected on Ti– Nb alloys and cp-Ti in artificial saliva and lactic acid solutions. The cytotoxicity of Ti– Nb alloys was comparable to that of cp-Ti in MC3T3-E1 pre-osteoblasts without interference from differentiation behaviour, but the proliferation rate of the Ti–5Nb alloy was lower than other groups. In overall, binary Ti–(10–25 wt%)Nb alloys are promising candidate for orthopaedic and dental implants due to their improved mechanical properties and comparable biological performance, while Ti–5Nb should be used with caution.
机译:由于低的杨氏模量和无毒特性,二元钛铌铌(Ti-Nb)合金最近受到了人们的关注。这项研究探索了低Nb含量(0–25 wt%)对拉伸应力-应变关系(最终强度(σ),屈服强度(σ)和弹性模量()),表面特性(维氏显微硬度)的综合参数的影响,表面粗糙度(),水接触角(WCA),X射线衍射(XRD)和扫描电子显微镜(SEM)),耐腐蚀性(在人造唾液和乳酸中)和生物学特性(MC3T3的细胞毒性和碱性磷酸酶活性) Ti-Nb合金(= 5、10、15、15、20和25 wt%)的-E1成骨细胞,并使用商业纯净的2级钛(cp-Ti)作为对照。 XRD结果表明,所有的Ti–Nb合金均包含α+βTi合金相,因此,随着Nb含量的增加,β相的增加(69-87 GPa的减少)。与cp-Ti相比,除Ti-5Nb以外,所有其他Ti-Nb合金均显示出明显更高的硬度,σ和σ的增加以及WCA的降低。在人造唾液和乳酸溶液中,未检测到Ti-Nb合金和cp-Ti腐蚀。在MC3T3-E1成骨细胞中,Ti-Nb合金的细胞毒性与cp-Ti相当,而没有分化行为的干扰,但Ti-5Nb合金的增殖速率低于其他组。总体而言,二元Ti–(10-25 wt%)Nb合金由于其改善的机械性能和可比的生物学性能而成为骨科和牙科植入物的有前途的候选者,而应谨慎使用Ti-5Nb。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号