首页> 美国卫生研究院文献>Journal of Cardiology Cases >A 60-year-old with heart failure symptoms due to 1st degree AV-Block caused by granulomatosis with polyangiitis (Wegener’s granulomatosis)
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A 60-year-old with heart failure symptoms due to 1st degree AV-Block caused by granulomatosis with polyangiitis (Wegener’s granulomatosis)

机译:一位60岁的老人因肉芽肿病和多血管炎(韦格纳肉芽肿病)引起的1级房室传导阻滞而出现心力衰竭症状

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摘要

Granulomatosis with polyangiitis is a rare systemic inflammatory disorder mainly affecting the small vessels. Cardiac involvement is rare, conduction delay being the most rare one. This case reports on a middle-aged male patient with heart failure symptoms due to a 1st degree atrioventricular block with a marked PR prolongation of 480 ms on electrocardiography (ECG). Because of heart failure symptoms as well as elevated N-terminal pro-B-type natriuretic peptide and no other relevant findings in the blood test it was initially planned to treat the conduction disorder with a pacemaker. During further investigations a certain diagnosis of granulomatosis with polyangiitis was determined. After administration of high-dose steroids a complete clinical remission of heart failure symptoms and normal conduction on ECG were demonstrated, so that no pacemaker therapy was needed.
机译:肉芽肿性多血管炎是一种罕见的全身性炎症性疾病,主要影响小血管。心脏受累很少见,传导延迟是最罕见的。该病例报告了一名中度男性患者,由于1级房室传导阻滞导致心力衰竭症状,心电图(ECG)显着PR延长480毫秒。由于心力衰竭症状以及N端前B型利尿钠肽水平升高,并且在血液测试中没有其他相关发现,因此最初计划使用起搏器治疗传导障碍。在进一步的研究中,确定了肉芽肿合并多血管炎的诊断。服用高剂量类固醇后,已证明可完全缓解心力衰竭症状并在ECG上正常传导,因此无需起搏器治疗。

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