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Development Of Novel Liposome-Encapsulated Combretastatin A4 Acylated Derivatives: Prodrug Approach For Improving Antitumor Efficacy

机译：新型脂质体包裹的Combretastatin A4酰化衍生物的开发：前药方法以提高抗肿瘤功效。

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期刊名称 International Journal of Nanomedicine
作者
Yongwei Gu; Juanjuan Ma; Zhiqin Fu; Youfa Xu; Baoan Gao; Jianzhong Yao; Wei Xu; Kedan Chu; Jianming Chen;
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作者单位

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年(卷),期 2019(14),-1
年度 2019
页码 -1
总页数 14
原文格式 PDF
正文语种
中图分类生化遗传学;生化药理学;
关键词
combretastatin A4; liposome; prodrug; drug release; anticancer;

机译：康他汀A4;脂质体;前药;药物释放;抗癌;

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专利

1. Development Of Novel Liposome-Encapsulated Combretastatin A4 Acylated Derivatives: Prodrug Approach For Improving Antitumor Efficacy [J] . Yongwei Gu, Juanjuan Ma, Zhiqin Fu, International Journal of Nanomedicine . 2019,第1期

机译：新型脂质体封装的组合A4酰化衍生物的发展：提高抗肿瘤功效的前药方法
2. Liposome formulations of combretastatin a4 and its 4-arylcoumarin analogue prodrugs: The antitumor effect in the mouse model of breast cancer [J] . Moiseevaa E.V., Kuznetsovaa N.R., Svirshchevskayaa E.V., Biochemistry (Moscow). Supplement, Series B. Biomedical chemistry . 2011,第3期

机译：康普他汀a4及其4-芳基香豆素类似物前体的脂质体制剂：在乳腺癌小鼠模型中的抗肿瘤作用
3. Development of a rapid and sensitive LC-MS/MS assay for the determination of combretastatin A4 phosphate, combretastatin A4 and combretastatin A4 glucuronide in beagle dog plasma and its application to a pharmacokinetic study [J] . Wang XJ, Chen ZH, Che JJ, Journal of chromatography, B. Analytical technologies in the biomedical and life sciences . 2009,第30期

机译：一种快速灵敏的LC-MS / MS测定方法，用于测定比格犬血浆中的磷酸康维他汀A4，康贝他汀A4和康维他汀A4葡糖苷酸及其在药代动力学研究中的应用
4. UNREVEALING PHASE I METABOLISM OF COMBRETASTATIN A4 BY A MULTI-TOOL MS-BASED APPROACH [C] . Karol Jaroch, Paulina Zofia Gorynska, Krzysztof Gorynski, International Mass Spectrometry Conference . 2018

机译：通过多工具基于MS的方法，揭开阶段I代谢A4
5. The synthesis of novel phosphate diester prodrugs of combretastatin A4; DNA cleavage with a metal ion-iminodiacetic acid linked deoxyoligonucleotide system or by photoreaction with 4-amino-1,8-naphthalimides. [D] . Jonklaas, Mark Devanand. 2003

机译：康普他汀A4的新型磷酸二酯前药的合成；用金属离子-亚氨基二乙酸连接的脱氧寡核苷酸系统或与4-氨基-1,8-萘二甲酰亚胺光反应进行DNA切割。
6. Magnetic resonance imaging and spectroscopy of combretastatin A4 prodrug-induced disruption of tumour perfusion and energetic status [O] . 1998

机译：康他汀A4前药对肿瘤灌注和能量状态的破坏的磁共振成像和光谱学
7. >Development Of Novel Liposome-Encapsulated Combretastatin A4 Acylated Derivatives: Prodrug Approach For Improving Antitumor Efficacy [O] . Yongwei Gu, Juanjuan Ma, Zhiqin Fu, 2019

机译：>新型脂质体封装的植物A4酰化衍生物的开发：提高抗肿瘤效力的前药方法
8. Novel Approach for Effectively Treating SCI Pain, Improving Opioid Efficacy, and Preventing Opioid Induced Constipation: Key Role of Toll-Like Receptor 4 (TLR4). [R] . Watkins, L. 2016

机译：有效治疗sCI疼痛，提高阿片类药物功效，预防阿片类药物引起的便秘的新方法：Toll样受体4（TLR4）的关键作用。

Development Of Novel Liposome-Encapsulated Combretastatin A4 Acylated Derivatives: Prodrug Approach For Improving Antitumor Efficacy

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