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Conditional survival and recurrence of remnant gastric cancer after surgical resection: A multi‐institutional study

机译:手术切除后残留胃癌的条件生存和复发:一项多机构研究

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摘要

The present study was designed to evaluate the dynamic survival and recurrence of remnant gastric cancer (RGC) after radical resection and to provide a reference for the development of personalized follow‐up strategies. A total of 298 patients were analyzed for their 3‐year conditional overall survival (COS3), 3‐year conditional disease‐specific survival (CDSS3), corresponding recurrence and pattern changes, and associated risk factors. The 5‐year overall survival (OS) and the 5‐year disease‐specific survival (DSS) of the entire cohort were 41.2% and 45.8%, respectively. The COS3 and CDDS3 of RGC patients who survived for 5 years were 84.0% and 89.8%, respectively. The conditional survival in patients with unfavorable prognostic characteristics showed greater growth over time than in those with favorable prognostic characteristics (eg, COS3, ≥T3: 46.4%‐83.0%, Δ36.6% vs ≤T2: 82.4%‐85.7%, Δ3.3%;  P > 0.05). Time‐dependent logistic regression analysis showed that the AJCC stage independently affected recurrence within 2 years after surgery (
机译:本研究旨在评估根治性切除术后残余胃癌(RGC)的动态生存和复发情况,并为制定个性化随访策略提供参考。总共对298例患者进行了3年条件总生存期(COS3),3年条件疾病特异性生存期(CDSS3),相应的复发和模式变化以及相关危险因素的分析。整个队列的5年总体生存率(OS)和5年疾病特异性生存率(DSS)分别为41.2%和45.8%。存活5年的RGC患者的COS3和CDDS3分别为84.0%和89.8%。预后不良的患者的条件生存期随时间的增长比预后良好的患者(例如COS3,≥T3:46.4%-83.0%,Δ36.6%vs≤T2:82.4%-85.7%,Δ3 .3%; P> 0.05)。基于时间的逻辑回归分析显示,AJCC分期独立影响术后2年内的复发(

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