Reconstruction and analysis of a carbon-core metabolic network for Dunaliella salina

摘要

Microalgae received increased attention over recent years due to their ability to produce high-value compounds such as polyunsaturated fatty acids and carotenoids [ – ]. Optimizing microalgal growth and product compositions in order to facilitate economically feasible mass production is still challenging. A better understanding of the complex algal metabolism is an important prerequisite overcoming this hurdle. In regards to algal metabolism, the halophilic unicellular green alga is an excellent model organism to investigate changes in metabolism [ ] as the physiology of the switch from primary growth to secondary stress metabolism with glycerol and carotenoid accumulation is very well known [ – ]. In addition, remains one of the few microalgae currently being commercialized for -carotene production on a large scale [ ].