Glutamate receptors on myelinated spinal cord axons: I) GluR6 kainate receptors

摘要

Objective:The deleterious effects of glutamate excitoxicity are well described for CNS gray matter. While overactivation of glutamate receptors also contributes to axonal injury, the mechanisms are poorly understood. Our goal was to elucidate the mechanisms of kainate receptor-dependent axonal Ca²⁺ deregulation.