Resins with Identical Specifications are not Identical. Identifying a Useful Solid-Phase Resin

摘要

The quality of the most commonly used support for solid phase syntheses, polystyrene resin cross linked with 1% of divinylbenzene, differs considerably even among different lots of resin from the same source. Determination of the swelling capacity of resins before carrying out solid-phase synthesis represents a very simple means of nondestructive pre-synthetic resin characterization.