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The Interplay of Public Intervention and Private Choices in Determining the Outcome of Vaccination Programmes

机译:公共干预及私人选择在确定疫苗接种计划的成果的互动性

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摘要

After a long period of stagnation, traditionally explained by the voluntary nature of the programme, a considerable increase in routine measles vaccine uptake has been recently observed in Italy after a set of public interventions aiming to promote MMR immunization, whilst retaining its voluntary aspect. To account for this take-off in coverage we propose a simple SIR transmission model with vaccination choice, where, unlike similar works, vaccinating behaviour spreads not only through the diffusion of “private” information spontaneously circulating among parents of children to be vaccinated, which we call imitation, but also through public information communicated by the public health authorities. We show that public intervention has a stabilising role which is able to reduce the strength of imitation-induced oscillations, to allow disease elimination, and to even make the disease-free equilibrium where everyone is vaccinated globally attractive. The available Italian data are used to evaluate the main behavioural parameters, showing that the proposed model seems to provide a much more plausible behavioural explanation of the observed take-off of uptake of vaccine against measles than models based on pure imitation alone.
机译:在长期停滞之后,传统上由该计划的自愿性质来解释,最近在意大利采取了一系列旨在促进MMR免疫同时保持其自愿性的公共干预措施之后,常规麻疹疫苗的使用量显着增加。为了解决这种覆盖率上升的问题,我们提出了一个带有疫苗接种选择的简单SIR传播模型,与类似的作品不同,疫苗接种行为的传播不仅是通过在待接种儿童的父母之间自发传播的“私人”信息的传播,我们称其为模仿,但也可以通过公共卫生部门传达的公共信息来进行。我们表明,公共干预具有稳定作用,能够降低模仿引起的振荡的强度,消除疾病,甚至使每个人都接受全球疫苗接种的无病平衡变得有吸引力。可用的意大利数据用于评估主要行为参数,表明与仅基于单纯模仿的模型相比,所提出的模型似乎为观察到的针对麻疹的疫苗摄取量提供了更为合理的行为解释。

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