Efficacy of ipamorelin a ghrelin mimetic on gastric dysmotility in a rodent model of postoperative ileus

摘要

BackgroundDelayed gastric emptying is a common disorder with few effective therapeutic options. The goal of this study was to investigate whether ipamorelin, a synthetic peptidomimetic that acts on the ghrelin receptor, accelerates gastric emptying in a rodent model of gastroparesis induced by abdominal surgery and intestinal manipulation.