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18FFLT PET for Non-Invasive Assessment of Tumor Sensitivity to Chemotherapy: Studies with Experimental Chemotherapy TP202377 in Human Cancer Xenografts in Mice

机译：18 F FLT pET为肿瘤细胞敏感性的非侵入性评估对化疗：研究与实验性化疗Tp202377在人癌异种移植物的小鼠中

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Aim3′-deoxy-3′-[¹⁸F]fluorothymidine ([18F]FLT) is a tracer used to assess cell proliferation in vivo. The aim of the study was to use [18F]FLT positron emission tomography (PET) to study non-invasively early anti-proliferative effects of the experimental chemotherapeutic agent TP202377 in both sensitive and resistant tumors.

机译：Aim3'-脱氧-3'-[^{18 F]氟胸苷（[18F] FLT）是用于评估体内细胞增殖的示踪剂。这项研究的目的是使用[18F] FLT正电子发射断层扫描（PET）研究实验性化疗药物TP202377在敏感和耐药肿瘤中的非侵入性早期抗增殖作用。}

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Mette Munk Jensen; Kamille Dumong Erichsen; Fredrik Björkling; Jacob Madsen; Peter Buhl Jensen; Maxwell Sehested; Liselotte Højgaard; Andreas Kjær;
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年(卷),期 -1(7),11
年度 -1
页码 e50618
总页数 9
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1. Clinical relevance of human cancer xenografts as a tool for preclinical assessment: example of in-vivo evaluation of topotecan-based chemotherapy in a panel of human small-cell lung cancer xenografts. [J] . Nemati F, Daniel C, Arvelo Anti-cancer drugs . 2010,第1期

机译：人类癌症异种移植物作为临床前评估工具的临床相关性：一组人类小细胞肺癌异种移植物中基于拓扑替康的化疗的体内评估实例。
2. Xenografts of primary human gynecological tumors grown under the renal capsule of NOD/SCID mice show genetic stability during serial transplantation and respond to cytotoxic chemotherapy. [J] . Press JZ, Kenyon JA, Xue H, Gynecologic Oncology: An International Journal . 2008,第2期

机译：在NOD / SCID小鼠肾脏包膜下生长的人类原发性妇科肿瘤的异种移植在连续移植过程中显示出遗传稳定性，并对细胞毒性化学疗法有反应。
3. Experimental study of the vascular normalization window for tumors treated with apatinib and the efficacy of sequential chemotherapy with apatinib in lung cancer‐bearing mice and patients [J] . Mingtao Liu, Hui Li, Xiuxiu Wang, Cancer Medicine . 2020,第8期

机译：血管标准化窗口对血管血管血管标准化窗口的实验研究及序贯化疗与肺癌轴承小鼠和患者的疗效
4. Evaluation of Antitumor Activity of Doxorubicin-Loaded Triblock Micelles in 3-D Multicellular Spheroids and Tumor-bearing Mouse Models for Cancer Chemotherapy [C] . T.H.Kim, C. Mount, T. Goodman, Annual meeting exposition of the Controlled Release Society . 2010

机译：阿霉素三嵌段胶束在3-D多细胞球体和荷瘤小鼠模型中的抗癌活性的癌症化疗的评价。
5. Non-invasive in vivo assessment of tumor hypoxia using functional magnetic resonance (fMR) imaging during therapy in human head and neck squamous cell carcinoma (HNSCC) xenografts: Implications for assessing therapeutic efficacy. [D] . Bhattacharya, Arup. 2005

机译：在人头颈部鳞状细胞癌（HNSCC）异种移植物治疗期间，使用功能性磁共振（fMR）成像对肿瘤缺氧进行非侵入性体内评估：评估治疗功效的意义。
6. 18FDG 18FFLT 18FFAZA and 11C-Methionine Are Suitable Tracers for the Diagnosis and In Vivo Follow-Up of the Efficacy of Chemotherapy by miniPET in Both Multidrug Resistant and Sensitive Human Gynecologic Tumor Xenografts [O] . György Trencsényi, Teréz Márián, Imre Lajtos, -1

机译：18FDG18F FLT18F FAZA和11C-蛋氨酸是适用于多药耐药和敏感性人类妇科肿瘤异种移植物中miniPET进行化学疗法的诊断和体内随访的示踪剂
7. [18F]FLT PET for non-invasive assessment of tumor sensitivity to chemotherapy: studies with experimental chemotherapy TP202377 in human cancer xenografts in mice. [O] . Mette Munk Jensen, Kamille Dumong Erichsen, Fredrik Björkling, 2012

机译：[18F] FLT pET用于非侵入性评估肿瘤对化疗的敏感性：用小鼠人癌异种移植物中的实验化学疗法Tp202377进行的研究。
8. Non-invasive PET Imaging of Human Breast Xenografts: Influence of Tumor Hypoxia [R] . Ling, C. C. 2000

机译：人乳腺异种移植物的非侵入性pET成像：肿瘤缺氧的影响

18FFLT PET for Non-Invasive Assessment of Tumor Sensitivity to Chemotherapy: Studies with Experimental Chemotherapy TP202377 in Human Cancer Xenografts in Mice

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