Xuezhikang Extract of Red Yeast Rice Improved Abnormal Hemorheology Suppressed Caveolin-1 and Increased eNOS Expression in Atherosclerotic Rats

摘要

BackgroundXuezhikang is the extract of red yeast rice, which has been widely used for the management of atherosclerotic disease, but the molecular basis of its antiatherosclerotic effects has not yet been fully identified. Here we investigated the changes of eNOS in vascular endothelia and RBCs, eNOS regulatory factor Caveolin-1 in endothelia, and hemorheological parameters in atherosclerotic rats to explore the protective effects of Xuezhikang.