Highly Z-Selective and Enantioselective Ring Opening/Cross Metathesis Catalyzed by Resolved Stereogenic-At-Ru Complex

摘要

The synthesis of a ruthenium complex that catalyzes Z-selective (up to 98% Z) asymmetric ring opening/cross metathesis with high enantioselectivity (up to 95% ee) is reported. Synthesis of the catalyst features the resolution of a chelating NHC alkylidene complex by ligand substitution with a chiral carboxylate.