Comparison of Frozen and Unfrozen Blood Spots for Gene Expression Studies

摘要

We studied gene expression in nine sets of paired newborn blood spots stored for 8–10 years in either the frozen or unfrozen state. Fewer genes were expressed in unfrozen spots, but the average correlation coefficient for overall gene expression comparing the frozen and unfrozen state was 0.771 (95% CI: [0.700–0.828]).