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Comprehensive biomarker analysis and final efficacy results of sorafenib in the BATTLE (Biomarker-Integrated Approaches of Targeted Therapy for Lung Cancer Elimination) trial

机译：索拉非尼在BATTLE（针对肺癌的靶向治疗的生物标志物整合方法）试验中的全面生物标志物分析和最终疗效结果

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PurposeTo report the clinical efficacy of sorafenib and to evaluate biomarkers associated with sorafenib clinical benefit in the BATTLE program.

机译：目的在BATTLE计划中报告索拉非尼的临床疗效并评估与索拉非尼临床获益相关的生物标志物。

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作者
George R. Blumenschein Jr.; Pierre Saintigny; Suyu Liu; Edward S. Kim; Anne S. Tsao; Roy S. Herbst; Christine Alden; J. Jack Lee; Ximing Tang; David J. Stewart; Merrill S. Kies; Frank V. Fossella; Hai T. Tran; L. Mao; Marshall E. Hicks; Jeremy Erasmus Jr.; Sanjay Gupta; Luc Girard; Michael Peyton; Lixia Diao; Jing Wang; Suzanne E. Davis; John Minna; Ignacio Wistuba; Waun K. Hong; John V. Heymach; Scott M. Lippman;
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年(卷),期 -1(19),24
年度 -1
页码 6967–6975
总页数 18
原文格式 PDF
正文语种
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关键词
multikinase inhibitor non–small cell lung cancer sorafenib biomarkers targeted treatment;

机译：多激酶抑制剂;非小细胞肺癌;索拉非尼;生物标志物;靶向治疗;

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专利

1. Comprehensive biomarker analysis and final efficacy results of sorafenib in the BATTLE trial [J] . BlumenscheinG.R., SaintignyP., LiuS., Clinical cancer research: an official journal of the American Association for Cancer Research . 2013,第24期

机译：索拉非尼在BATTLE试验中的综合生物标志物分析和最终疗效结果
2. The BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer [J] . Papadimitrakopoulou Vassiliki, Lee J. Jack, Wistuba Ignacio I., Journal of Clinical Oncology . 2016,第30期

机译：BATTLE-2研究：针对先前接受治疗的晚期非小细胞肺癌患者的生物标志物靶向治疗研究
3. The BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer [J] . Papadimitrakopoulou Vassiliki, Lee J. Jack, Wistuba Ignacio I., Journal of Clinical Oncology . 2016,第30期

机译：Battle-2研究：在先前治疗的晚期非小细胞肺癌患者中，生物标志物综合靶向治疗研究
4. Biomarker driven target therapy trial in gastric cancer [C] . Cho JY, Lim JY International Gastric Cancer Congress . 2011

机译：生物标志物驱动胃癌靶治疗试验
5. Predictive Biomarkers of the Efficacy of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Treating Advanced Non-small Cell Lung Cancer: A Systematic Review of Randomized Controlled Trials [D] . Yang, Zuyao. 2014

机译：表皮生长因子受体酪氨酸激酶抑制剂治疗晚期非小细胞肺癌疗效的预测生物标志物：随机对照试验的系统评价。
6. The BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non–Small-Cell Lung Cancer [O] . Vassiliki Papadimitrakopoulou, J. Jack Lee, Ignacio I. Wistuba, -1

机译：BATTLE-2研究：针对先前接受治疗的晚期非小细胞肺癌患者的生物标志物靶向治疗研究
7. Comprehensive Biomarker Analysis and Final Efficacy Results of Sorafenib in the BATTLE Trial [O] . George R. Blumenschein, Pierre Saintigny, Suyu Liu, 2013

机译：战斗试验中索拉非尼的综合生物标志物分析及最终疗效结果
8. BATTLE (Biomarker-based Approaches of Targeted Therapy for Lung Cancer Elimination) [R] . Hong, W. K. 2011

机译：BaTTLE（基于生物标志物的靶向治疗肺癌消除方法）

Comprehensive biomarker analysis and final efficacy results of sorafenib in the BATTLE (Biomarker-Integrated Approaches of Targeted Therapy for Lung Cancer Elimination) trial

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