IP-10 a Potential Driver of Neurally-Controlled IL-10 and Morbidity in Human Blunt Trauma

摘要

ObjectiveBlunt trauma and traumatic spinal cord injury (TSCI) induce systemic inflammation that contributes to morbidity. Dysregulated neural control of systemic inflammation post-injury is likely exaggerated in patients with TSCI. We utilized in silico methods to discern dynamic inflammatory networks that could distinguish systemic inflammation in TSCI from blunt trauma.