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Cognitive training for children with ADHD: a randomized controlled trial of cogmed working memory training and ‘paying attention in class’

机译:针对多动症儿童的认知训练:关于工作记忆训练和在课堂上注意的随机对照试验

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摘要

The goal of this randomized controlled trial was to replicate and extend previous studies of Cogmed Working Memory Training (CWMT) in children with Attention-deficit/hyperactivity disorder (ADHD). While a large proportion of children with ADHD suffer from academic difficulties, only few previous efficacy studies have taken into account long term academic outcome measures. So far, results regarding academic outcome measures have been inconsistent. Hundred and two children with ADHD between the age of 8 and 12 years (both medicated and medication naïve) participated in current randomized controlled trial. Children were randomly assigned to CWMT or a new active combined working memory- and executive function compensatory training called ‘Paying Attention in Class.’ Primary outcome measures were neurocognitive functioning and academic performance. Secondary outcome measures contained ratings of behavior in class, behavior problems, and quality of life. Assessment took place before, directly after and 6 months after treatment. Results showed only one replicated treatment effect on visual spatial working memory in favor of CWMT. Effects of time were found for broad neurocognitive measures, supported by parent and teacher ratings. However, no treatment or time effects were found for the measures of academic performance, behavior in class or quality of life. We suggest that methodological and non-specific treatment factors should be taken into account when interpreting current findings. Future trials with well-blinded measures and a third ‘no treatment’ control group are needed before cognitive training can be supported as an evidence-based treatment of ADHD. Future research should put more effort into investigating why, how and for whom cognitive training is effective as this would also potentially lead to improved intervention- and study designs.
机译:这项随机对照试验的目的是复制和扩展先前对注意力缺陷多动障碍(ADHD)儿童进行的Cogmed工作记忆训练(CWMT)的研究。尽管很大一部分患有ADHD的儿童都患有学业上的困难,但只有很少的先前功效研究考虑了长期的学业成果指标。到目前为止,关于学术成果评估的结果一直不一致。一百零二名8岁至12岁之间患有ADHD的儿童(包括药物治疗和纯药物治疗)参加了当前的随机对照试验。将儿童随机分配到CWMT或新的主动工作记忆和执行功能补偿培训(称为“课堂上的注意力集中”)中。主要的结局指标是神经认知功能和学习成绩。次要结局指标包括班级行为,行为问题和生活质量的等级。评估在治疗之前,之后和之后六个月进行。结果表明,仅对CWMT有一种对视觉空间工作记忆的重复治疗效果。在父母和老师的评分支持下,发现时间对广泛的神经认知测量有影响。但是,没有发现任何治疗或时间效应可用于衡量学业成绩,课堂行为或生活质量。我们建议在解释当前发现时应考虑方法学和非特异性治疗因素。在将认知训练作为基于证据的多动症治疗方法得到支持之前,需要对盲法和第三个“不治疗”对照组进行进一步的试验。未来的研究应投入更多精力研究为什么,如何以及对谁进行认知培训有效,因为这也有可能导致改善干预和研究设计。

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