Enhanced neointimal fibroblast myofibroblast content and altered extracellular matrix composition: Implications in the progression of human peripheral artery restenosis

摘要

Background and aimsNeointimal cellular proliferation of fibroblasts and myofibroblasts is documented in coronary artery restenosis, however, their role in peripheral arterial disease (PAD) restenosis remains unclear. Our aim was to investigate the role of fibroblasts, myofibroblasts, and collagens in restenotic PAD.