A single-institution comparison of cetuximab carboplatin and paclitaxel induction chemotherapy followed by chemoradiation (CRT) versus CRT for locally-advanced squamous cell carcinoma of the head and neck (LA-SCCHN)

摘要

ObjectivesComparisons of induction chemotherapy (IC) against upfront chemoradiation (CRT) for locally advanced head and neck cancer (LA-HNSCC) have demonstrated no differences except greater toxicity with IC. Effective induction regimens that are less toxic are therefore warranted. To inform future efforts with IC, we present our institutional experience comparing a less toxic IC regimen to CRT.