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The impact of an IUD and implant intervention on dual method use among young women: Results from a cluster randomized trial

机译:宫内节育器和植入物干预对年轻女性双重使用方法的影响:一项整群随机试验的结果

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摘要

Long-acting reversible contraceptives (LARCs) are highly effective at preventing pregnancy but do not protect against sexually transmitted infection (STI). Recent efforts to improve access to intrauterine devices (IUDs) and implants have raised concerns about STI prevention and reduced condom use, particularly among teenagers and young women. We evaluated whether a provider-targeted intervention to increase LARC access negatively impacted dual method use and STI incidence among an at-risk patient population.We conducted a cluster randomized trial in 40 reproductive health centers across the United States from May 2011 to May 2013. After training providers at 20 intervention sites, we recruited 1500 sexually-active women aged 18–25 years who did not desire pregnancy and followed them for one year. We assessed intervention effects on dual method use, condom use and STI incidence, modeling dual method use with generalized estimating equations and STI incidence with Cox proportional hazard regression models, accounting for clustering.We found no differences between intervention and control groups in dual method use (14.3% vs. 14.4%, aOR 1.03, 95% CI 0.74–1.44) or condom use (30% vs. 31%, aOR 1.03, 95% CI 0.79–1.35) at last sex at one year. STI incidence was 16.5 per 100 person-years and did not differ between intervention and control groups (aHR 1.20, 95% CI 0.88–1.64).A provider training intervention to increase LARC access neither compromised condom use nor increased STI incidence among young women. Dual method use was very low overall, highlighting the need to bolster STI prevention efforts among adolescents and young women.
机译:长效可逆避孕药(LARCs)在预防怀孕方面非常有效,但不能预防性传播感染(STI)。最近为改善宫内节育器和植入物的可及性所做的努力引起了人们对预防性传播感染和减少使用避孕套的担忧,特别是在青少年中。我们评估了以提供者为目标的干预措施以增加LARC的使用是否对高危患者人群的双重方法使用和STI发生率产生负面影响.2011年5月至2013年5月,我们在美国40个生殖健康中心进行了一项随机分组试验。在20个干预点培训了提供者之后,我们招募了1500名18-25岁不希望怀孕的性活跃妇女,并对她们进行了为期一年的随访。我们评估了干预措施对双重使用方法,避孕套使用和性传播疾病发病率的影响,采用广义估计方程对双重方法使用进行建模,并通过Cox比例风险回归模型对STI发生率进行了建模,并进行了聚类分析。 (14.3%vs. 14.4%,aOR 1.03,95%CI 0.74–1.44)或安全套使用(30%vs. 31%,aOR 1.03,95%CI 0.79–1.35)一年时做爱。 STI发生率为每100人年16.5,干预组与对照组之间无差异(aHR 1.20,95%CI 0.88-1.64)。提供者培训干预措施可以增加LARC的使用率,既不影响避孕套的使用,也不增加年轻女性的STI发生率。双重方法的总体使用率非常低,突出表明需要加强青少年和年轻妇女的性传播感染预防工作。

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