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A novel device for collecting and dispensing fingerstick blood for point of care testing

机译:一种新颖的用于采集和分配指尖血液以进行即时护理测试的设备

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摘要

The increased world-wide availability of point-of-care (POC) tests utilizing fingerstick blood has led to testing scenarios in which multiple separate fingersticks are performed during a single patient encounter, generating cumulative discomfort and reducing testing efficiency. We have developed a device capable of a) collection of up to 100 μL of fingerstick blood from a single fingerstick by capillary action, and b) dispensing this blood in variable increments set by the user. We tested the prototype device both in a controlled laboratory setting and in a fingerstick study involving naive device users, and found it to have accuracy and precision similar to a conventional pipettor. The users also found the device to be easy to use, and recommended minor ergonomic improvements. Our device would allow performance of multiple POC tests from a single fingerstick blood sample, thus providing a novel functionality that may be of use in many testing settings worldwide.
机译:利用指尖血液在全球范围内进行即时医疗(POC)测试的可用性不断提高,导致了测试场景,即在单个患者遭遇期间要使用多个单独的指尖,从而产生累积的不适感并降低了测试效率。我们开发了一种设备,该设备能够a)通过毛细作用从单个指尖收集多达100μL指尖血液,并b)以用户设定的可变增量分配这种血液。我们在受控实验室环境中进行了原型设备的测试,并在涉及朴素设备用户的指尖研究中对其进行了测试,发现该设备具有与传统移液器相似的准确性和精密度。用户还发现该设备易于使用,并建议对人体工学进行较小的改进。我们的设备将允许从一个指尖的血液样本中执行多个POC测试,从而提供一种新颖的功能,该功能可能会在全球许多测试环境中使用。

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