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Cocoon devices for transcatheter closure of atrial septal defect and patent ductus arteriosus in children

机译:小儿房间隔缺损和动脉导管未闭经导管封闭的茧装置

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Closure of the atrial septal defect (ASD) and patent ductus arteriosus (PDA) are among the most frequent cardiac interventional procedures. This was a prospective study, which started together with the implementation of a national program of pediatric interventional cardiology in Romania. We used Cocoon devices in 83 consecutive cases from 92 implantations for ASD and PDA. 27 cases were ASD closure and 56 cases PDA closure. Regarding the ASD closure, the median age was 8.5 years (range 3–25 years) and median weight 25 kg (range 11.5–63 kg). The mean follow-up was 17.4 ± 6.7 months (range 3–26 months). The mean ASD diameter by transesophageal echocardiography was 15.2 ± 4.1 mm (range 8–26 mm). The mean device diameter used was 17.3 ± 5.6 mm (range 8–32 mm). Regarding the PDA closure, the median age was 36 months (range 4–192 months) and median weight 14 kg (range 5–58 kg). The mean follow-up was 15 ± 8 months (range 3–28 months). The mean PDA minimum diameter was 2.5 ± 0.8 mm. The success implantation rate for both groups was 97.6% (2 cases of withdrawn for ASD and PDA), while the complication rate was 2.3% (including 2 ASD device embolization). In the first 24 hours, the closure rates were 96.3% for ASD, 98.2% for PDA, and 100% at 1-month follow-up for both procedures. On short and intermediate follow-up (3–28 months), no device-related complications were noted.The Cocoon devices are safe for transcatheter closure of both ASD and PDA, and the initial experience with their use in our emerging center is encouraging.
机译:房间隔缺损(ASD)和动脉导管未闭(PDA)的闭合是最常见的心脏介入手术。这是一项前瞻性研究,始于在罗马尼亚实施国家小儿介入性心脏病学计划。我们在92例ASD和PDA植入物中连续83例使用了Cocoon设备。 ASD封​​堵27例,PDA封堵56例。关于ASD封堵术,中位年龄为8.5岁(3-25岁),中位体重为25 kg(11.5-63 kg)。平均随访17.4±6.7个月(3–26个月)。经食道超声心动图检查的平均ASD直径为15.2±4.1毫米(8-26毫米)。所使用的平均装置直径为17.3±5.6毫米(8-32毫米)。关于PDA封堵,中位年龄为36个月(4–192个月),中位体重为14 kg(5–58 kg)。平均随访时间为15±8个月(范围3–28个月)。 PDA的平均最小直径为2.5mm±0.8mm。两组的成功植入率为97.6%(2例因ASD和PDA撤出),并发症发生率为2.3%(包括2例ASD装置栓塞术)。在最初的24小时内,两种手术的ASD闭合率为96.3%,PDA为98.2%,随访1个月为100%。在短期和中期随访(3–28个月)中,未发现与器械相关的并发症。Cocoon器械可安全关闭ASD和PDA的经导管,在我们的新兴中心使用它们的初步经验令人鼓舞。

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