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Lime (Citrus aurantifolia (Christm.) Swingle) Essential Oils: Volatile Compounds Antioxidant Capacity and Hypolipidemic Effect

机译:青柠(柑橘)(Swingle)香精油:挥发性化合物抗氧化能力和降血脂作用

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摘要

Lime peels are mainly obtained from the byproducts of the juice manufacturing industry, which we obtained and used to extract essential oil (2.3%) in order to examine the antioxidant and hypolipidaemic effects. We identified 60 volatile compounds of lime essential oil (LEO) with GC/MS, of which the predominant constituents were limonene, γ-terpinene, and β-pinene. Lime essential oil was measured according to the DPPH assay and ABTS assay, with IC50 values of 2.36 mg/mL and 0.26 mg/mL, respectively. This study also explored the protective effects of LEO against lipid-induced hyperlipidemia in a rat model. Two groups of rats received oral LEO in doses of 0.74 g/100 g and 2.23 g/100 g with their diets. Eight weeks later, we found that the administration of LEO improved the serum total cholesterol, triglyceride, low-density lipoprotein cholesterol, alanine aminotransferase, and aspartate transaminase levels in the hyperlipidemic rats (p < 0.05). Simultaneously, the LEO improved the health of the rats in terms of obesity, atherogenic index, and fatty liver.
机译:石灰皮主要来自果汁制造业的副产品,我们从中获得并用于提取香精油(2.3%)以检查其抗氧化和降血脂作用。我们通过GC / MS鉴定了60种石灰精油(LEO)的挥发性化合物,其中主要成分为柠檬烯,γ-萜品烯和β-pine烯。根据DPPH测定法和ABTS测定法测定了柠檬精油的IC50值分别为2.36 mg / mL和0.26 mg / mL。这项研究还探讨了LEO对大鼠脂质引起的高脂血症的保护作用。两组大鼠在饮食中分别接受0.74 g / 100 g和2.23 g / 100 g的口服LEO。八周后,我们发现在高脂血症大鼠中,LEO的使用可以改善血清总胆固醇,甘油三酸酯,低密度脂蛋白胆固醇,丙氨酸氨基转移酶和天冬氨酸转氨酶水平(p <0.05)。同时,LEO在肥胖,动脉粥样硬化指数和脂肪肝方面改善了大鼠的健康。

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