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Customized double‐shell immobilization device combined with VMAT radiation treatment of basosquamous cell carcinoma of the scalp

机译:定制化双壳固定装置结合VMAT放射治疗头皮鳞状细胞癌

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摘要

Malignancies with a superficial involvement of the scalp/skull present technical challenges for radiation‐treatment‐planning, such as achieving skin coverage with the prescribed dose and with the desirable conformity, homogeneity, and lower brain dose. We report a radiotherapy treatment technique for a patient diagnosed with diffuse basosquamous cell carcinoma of the scalp and adjacent skull‐bone. This study presents the plan's quality parameters, patient's dosimetry, and patient's outcome. The patient was treated using volume‐modulated‐arc therapy (VMAT) and a double‐shell‐bolus full‐head device (DSBFD) designed for patient immobilization and better skin coverage. A VMAT plan was generated using an Eclipse treatment‐planning system for a prescribed dose of 60 Gy in 30 fractions. The treatment plan was analyzed to determine the conformity index (CI), the homogeneity index (HI), the target‐coverage, and the dose to the organs‐at‐risk (OARs). Skin‐doses were measured using optically stimulated luminescence (OSL) dosimeters. Clinical follow‐up was performed by the radiation oncologist during and after the course of radiotherapy. With regard to planning target volume (PTV) coverage, the V 95 was 99%. The measured and calculated dose to the skin was in the range 100–108% of the prescribed dose. The mean brain‐PTV dose was 711 cGy. The CI and HI were 1.09 and 1.08, respectively. The mean positioning accuracy for the patient over the course of treatment was within 2 mm. The measured accumulated skin dose and planning dose was agreed within 2%. Clinical examination of the patient 6 months after radiotherapy showed good response to the treatment and a 90% reduction in scarring. The DSBFD technique combined with RapidArc treatment was useful in terms of the target dose distribution and coverage. Daily patient alignment was found very precise, reproducible and less time‐consuming.
机译:头皮/头骨表面受累的恶性肿瘤对放射治疗计划提出了技术挑战,例如以规定的剂量以及理想的顺应性,均匀性和较低的大脑剂量实现皮肤覆盖。我们报告了一种诊断为头皮及邻近颅骨弥漫性基底鳞状细胞癌的患者的放射治疗技术。这项研究介绍了该计划的质量参数,患者的剂量和患者的结局。使用容积调节电弧疗法(VMAT)和双壳推注式全头装置(DSBFD)对患者进行了治疗,旨在使患者固定并更好地覆盖皮肤。使用Eclipse治疗计划系统生成VMAT计划,以30分数的60 Gy的规定剂量使用。分析了治疗计划,以确定合格指数(CI),均匀性指数(HI),靶标覆盖率和高危器官剂量(OAR)。使用光学刺激发光(OSL)剂量计测量皮肤剂量。放疗过程中和放疗后由放射肿瘤学家进行临床随访。关于计划目标体积(PTV)的覆盖范围,V 95为99%。对皮肤的测量和计算剂量为处方剂量的100–108%。脑PTV的平均剂量为711 cGy。 CI和HI分别为1.09和1.08。患者在治疗过程中的平均定位精度在2毫米以内。测得的累积皮肤剂量和计划剂量在2%以内。放疗后6个月的患者临床检查显示对治疗的反应良好,疤痕减少了90%。 DSBFD技术与RapidArc治疗相结合在目标剂量分布和覆盖范围方面很有用。发现每天的患者对准非常精确,可重复且耗时较少。

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