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The potential toxic impact of different gadolinium-based contrast agents combined with 7-T MRI on isolated human lymphocytes

机译：不同g造影剂与7-T MRI结合对离体人淋巴细胞的潜在毒性影响

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摘要

BackgroundTo investigate a potentially amplifying genotoxic or cytotoxic effect of different gadolinium-based contrast agents (GBCAs) in combination with ultra-high-field 7-T magnetic resonance imaging (MRI) exposure in separated human peripheral blood lymphocytes.

机译：背景要研究不同g基造影剂（GBCA）与超高磁场7-T磁共振成像（MRI）暴露于分离的人外周血淋巴细胞中的潜在放大遗传毒性或细胞毒性作用。

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期刊名称 European Radiology Experimental
作者
Björn Friebe; Frank Godenschweger; Mahsa Fatahi; Oliver Speck; Dirk Roggenbuck; Dirk Reinhold; Annika Reddig;
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作者单位

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年(卷),期 2018(2),-1
年度 2018
页码 40
总页数 9
原文格式 PDF
正文语种
中图分类放射医学;影像诊断学;
关键词
Apoptosis Contrast media Lymphocytes Magnetic resonance imaging DNA damage;

机译：凋亡;造影剂;淋巴细胞;磁共振成像;DNA损伤;

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专利

1. The potential toxic impact of different gadolinium-based contrast agents combined with 7-T MRI on isolated human lymphocytes [J] . Bj?rn Friebe, Frank Godenschweger, Mahsa Fatahi, European Radiology Experimental . 2018,第1期

机译：不同g造影剂与7-T MRI结合对离体人淋巴细胞的潜在毒性影响
2. Gadolinium-Based MRI Contrast Agents Induce Mitochondrial Toxicity and Cell Death in Human Neurons, and Toxicity Increases With Reduced Kinetic Stability of the Agent [J] . Bower Danielle V., Richter Johannes K., von Tengg-Kobligk Hendrik, Investigative radiology . 2019,第8期

机译：基于钆的MRI造影剂诱导人类神经元的线粒体毒性和细胞死亡，并且毒性随着药剂的动力学稳定性降低而增加
3. Parallel Comparative Studies on Mouse Toxicity of Oxide Nanoparticle- and Gadolinium-Based T1 MRI Contrast Agents [J] . Chen Rui, Ling Daishun, Zhao Lin, ACS nano . 2015,第12期

机译：基于氧化物纳米粒子和d的T1 MRI造影剂对小鼠毒性的平行比较研究
4. Speciation Analysis of Gadolinium-Based MRI Contrast Agents in Human Body Fluids [C] . Lena Telgmann, Jens Kunnemeyer, F Faruk Tokmak, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2009

机译：人体液中钆的MRI对比剂的形态分析
5. Potential Environmental and Human Health Impacts of Rechargeable Lithium-Ion and Lithium Polymer Batteries in Discarded Cellular Phones: Evaluation of Hazardous Waste Classification, Resource Depletion Potential, Human Toxicity Potential, and Ecotoxicity Potential [D] . Kang, Daniel Hsing Po 2012

机译：废弃手机中可充电锂离子和锂聚合物电池对环境和人体健康的潜在影响：危险废物分类，资源耗竭潜力，人类毒性潜力和生态毒性潜力的评估
6. Responses of Human Skin in Organ Culture and Human Skin Fibroblasts to a Gadolinium-Based MRI Contrast Agent: Comparison of Skin from Patients with End-Stage Renal Disease and Skin from Healthy Subjects [O] . Marissa DaSilva, Monica O’Brien Deming, Suzanne E.G. Fligiel, -1

机译：人体皮肤在器官培养和人体皮肤成纤维细胞对基于钆的MRI造影剂中的反应：从健康受试者患有终末期肾病和皮肤患者的皮肤比较
7. Responses of Human Skin in Organ Culture and Human Skin Fibroblasts to a Gadolinium-Based MRI Contrast Agent [O] . Marissa DaSilva, Monica OʼBrien Deming, Suzanne E. G. Fligiel, 2010

机译：人体皮肤在器官培养和人体皮肤成纤维细胞中的酸碱基MRI造影剂的反应

The potential toxic impact of different gadolinium-based contrast agents combined with 7-T MRI on isolated human lymphocytes

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