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Genetic variants in p53 signaling pathway genes predict chemotherapy efficacy in colorectal cancer

机译：p53信号通路基因的遗传变异预测大肠癌的化疗效果

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BackgroundThe murine double minute‐2 gene (MDM2) was originally identified as predicting chemotherapy efficacy. However, little is known regarding the association between single nucleotide polymorphisms (SNPs) in the p53 signaling pathway and prognosis/chemotherapy sensitivity in colorectal cancer.

机译：背景鼠双分2基因（MDM2）最初被确定为可预测化学疗法的疗效。然而，关于p53信号通路中的单核苷酸多态性（SNP）与结直肠癌的预后/化学疗法敏感性之间的关联还知之甚少。

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期刊名称 Cancer Medicine
作者
Ke Zhang; Yixuan Meng; Xiangming Cao; Ye Xu; Mulong Du; Yuan Wu; Lingxiang Liu;
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作者单位

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年(卷),期 2019(8),7
年度 2019
页码 3428–3436
总页数 9
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
chemotherapy colorectal cancer genetic variants survival;

机译：化学疗法;大肠癌;遗传变异;生存;

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专利

1. Genetic variants in p53 signaling pathway genes predict chemotherapy efficacy in colorectal cancer [J] . Ke Zhang, Yixuan Meng, Xiangming Cao, Cancer Medicine . 2019,第7期

机译：p53信号通路基因的遗传变异预测大肠癌的化疗效果
2. Genetic variants in the Folic acid Metabolic Pathway Genes predict outcomes of metastatic Colorectal Cancer patients receiving first-line Chemotherapy [J] . Lu Jiang, Shuwei Li, Ming Yuan, Journal of Cancer . 2020,第22期

机译：叶酸代谢途径基因中的遗传变异预测接受一线化疗的转移结直肠癌患者的结果
3. Correlation between Gene Variants, Signaling Pathways, and Efficacy of Chemotherapy Drugs against Colon Cancers [J] . Swarnendu Tripathi, Louiza Belkacemi, Margaret S. Cheung, Cancer Informatics . 2016,第3期

机译：基因变异，信号通路和化学疗法药物对结肠癌的功效之间的相关性
4. Determination of EGFR and VEGF signaling pathway activity by immuno-MALDI to predict the outcome of targeted colorectal cancer (CRC) treatment [C] . Robert Popp, Andrew G. Chambers, Adriana Aguilar-Mahecha, ASMS Conference on Mass Spectrometry and Allied Topics . 2015

机译：免疫马尔迪的EGFR和VEGF信号通路活性预测靶向结直肠癌（CRC）治疗的结果
5. Molecular stress signaling in breast epithelial cells: Characterization of the regulation of the breast cancer susceptibility gene 1 (BCRA1) by stress signaling, and, Design of an epidemiological study examining the effect of glucocorticoid receptor genetic variants on breast cancer risk [D] . Antonova, Lilia 2008

机译：乳腺上皮细胞中的分子应激信号传递：通过应激信号传递来表征乳腺癌易感基因1（BCRA1）的调节，以及一项流行病学研究的设计，旨在研究糖皮质激素受体基因变异对乳腺癌风险的影响
6. Genetic variants in the Folic acid Metabolic Pathway Genes predict outcomes of metastatic Colorectal Cancer patients receiving first-line Chemotherapy [O] . Lu Jiang, Shuwei Li, Ming Yuan, 2020

机译：叶酸代谢途径基因中的遗传变异预测接受一线化疗的转移结直肠癌患者的结果
7. Genetic variants in the Folic acid Metabolic Pathway Genes predict outcomes of metastatic Colorectal Cancer patients receiving first-line Chemotherapy [O] . Lu Jiang, Shuwei Li, Ming Yuan, 2020

机译：叶酸代谢途径基因中的遗传变异预测接受一线化疗的转移结直肠癌患者的结果

Genetic variants in p53 signaling pathway genes predict chemotherapy efficacy in colorectal cancer

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