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Research and Global Health Emergencies: On the Essential Role of Best Practice

机译:研究与全球卫生紧急情况:最佳实践的基本作用

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摘要

This article addresses an important, overlooked regulatory challenge during global health emergencies (GHEs). It provides novel insights into how, and why, best practice can support decision makers in interpreting and implementing key guidance on conducting research during GHEs. The ability to conduct research before, during and after such events is crucial. The recent West-African Ebola outbreaks and the Zika virus have highlighted considerable room for improvement in meeting the imperative to research and rapidly develop effective therapies. A means of effectively capturing these experiences and folding them into future decision-making is lacking; the need for effective practical translational measures remains. The challenge for the research community lies in extracting meaningful action-guiding content from pre-existing guidelines—which draw upon practical examples of guidelines ‘in action’—that assist in determining how to act in a particular (future) situation. Insights are provided into the role of best practice as a means to do so; such examples can provide invaluable support to decision makers in interpreting high-level guidance; overarching guidelines retain their necessary level of generality and flexibility, whilst corresponding best practice examples—which incorporate important lessons learned—illustrate how such guidelines can be interpreted at a practical level.
机译:本文解决了全球卫生紧急情况(GHE)期间的一个重要而被忽视的监管挑战。它提供了关于最佳实践如何以及为何能够支持决策者解释和实施GHE期间进行研究的关键指导的新颖见解。在此类事件发生之前,之中和之后进行研究的能力至关重要。最近发生的西非埃博拉疫情和寨卡病毒突出表明,在满足研究和迅速发展有效疗法的需要方面,仍有很大的改进空间。缺乏有效吸收这些经验并将其纳入未来决策的方法;仍然需要有效的实际翻译措施。研究社区面临的挑战在于从预先存在的指南中提取有意义的行动指导内容,这些内容借鉴了“行动中”指南的实际示例,这些内容有助于确定如何在特定(未来)情况下采取行动。洞察最佳实践的作用,以此作为实现目标的手段;这样的例子可以为决策者解释高级指南提供宝贵的支持;总体指南保留了必要的一般性和灵活性,同时相应的最佳实践示例(结合了重要的经验教训)说明了如何在实践水平上解释此类指南。

著录项

  • 期刊名称 Public Health Ethics
  • 作者

    Nayha Sethi;

  • 作者单位
  • 年(卷),期 -1(11),3
  • 年度 -1
  • 页码 237–250
  • 总页数 14
  • 原文格式 PDF
  • 正文语种
  • 中图分类 公共卫生工程;
  • 关键词

  • 入库时间 2022-08-21 10:58:46

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