Abdominal DCE-MRI reconstruction with deformable motion correction for liver perfusion quantification

摘要

Purpose:Abdominal dynamic contrast-enhanced (DCE) MRI suffers from motion-induced artifacts that can blur images and distort contrast-agent uptake curves. For liver perfusion analysis, image reconstruction with rigid-body motion correction (RMC) can restore distorted portal-venous input functions (PVIF) to higher peak amplitudes. However, RMC cannot correct for liver deformation during breathing. We present a reconstruction algorithm with deformable motion correction (DMC) that enables correction of breathing-induced deformation in the whole abdomen.