A Non-invasive On-line Deuterium Dilution Technique for the Measurement of Total Body Water in Haemodialysis Patients

摘要

BackgroundDespite its importance, total body water (TBW) is usually estimated rather than measured due to the complexity of isotope dilution methods. The aim of this study was to demonstrate the applicability in haemodialysis (HD) patients of a recently developed on-line breath test, previously validated in healthy subjects, that uses the gold standard deuterium dilution method to measure TBW. In particular we wished to show that a pre-dialysis estimation was as good as a post dialysis equilibrated measurement in order to avoid patients needing to remain behind after dialysis treatment.