首页> 美国卫生研究院文献>The Journal of Infectious Diseases >Live Attenuated Zoster Vaccine Boosts Varicella Zoster Virus (VZV)–Specific Humoral Responses Systemically and at the Cervicovaginal Mucosa of Kenyan VZV-Seropositive Women

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Live Attenuated Zoster Vaccine Boosts Varicella Zoster Virus (VZV)–Specific Humoral Responses Systemically and at the Cervicovaginal Mucosa of Kenyan VZV-Seropositive Women

机译：减毒活的带状疱疹疫苗可增强水痘带状疱疹病毒（VZV）–肯尼亚VZV血清阳性女性的全身性和宫颈阴道粘膜特异性体液反应

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BackgroundAttenuated varicella zoster virus (VZV) is a promising vector for recombinant vaccines. Because human immunodeficiencyvirus (HIV) vaccines are believed to require mucosal immunogenicity, we characterized mucosal VZV-specific humoral immunity following VZVOka vaccination.

机译：背景减毒的水痘带状疱疹病毒（VZV）是用于重组疫苗的有前途的载体。因为人们认为人类免疫缺陷病毒（HIV）疫苗需要粘膜免疫原性，所以我们在接种VZVOka后表征了粘膜VZV特异性体液免疫。

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期刊名称 The Journal of Infectious Diseases
作者
Catia T Perciani; Manmeet Sekhon; Sabrina Hundal; Bashir Farah; Mario A Ostrowski; A Omu Anzala; Lyle R McKinnon; Walter Jaoko; Kelly S MacDonald; Dr Joshua Kimano; Dr Julius Oyugi; Dr Erastus Irungu; Jemima Nyakio; Roselyne Malogo; Rose Mahira; Dr Gaudensia Mutua; Dr Lydia Atambo; Dr Borna Nyaoke; Jacquelyn Nyange; Judith Omungo; Timothy Kotikot; Mary W Gichuho; Hilda Ogutu; Rose Ndambuki; Emmanuel Museve; Hannah Nduta Gakure; Dorothy Essendi; Elizabeth Mutiska; Brian Onsembe; Matrona Akiso; Simon Ogola; Nelly Wanjiku; Robert Langat; Jackton Indangasi; Naomi Mwakisha; Irene Mwangi; Marion Agwaya; Ruth Chirchir; Richard Alila; Lewa Said; James Wakonyo; Mercy Musanga; Catherine Kamau; Moses Muriuki; Jason Ndalamia; Catherine Ngeli; Laura Lusik;
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年(卷),期 -1(218),8
年度 -1
页码 1210–1218
总页数 9
原文格式 PDF
正文语种
中图分类免疫学;微生物学;病毒传染病;
关键词
varicella zoster virus zoster vaccine mucosal immunity vaccine vector HIV/AIDS vaccine;

机译：水痘带状疱疹;病毒;带状疱疹疫苗;粘膜免疫力;疫苗载体;HIV / AIDS疫苗;

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专利

1. Responses of varicella zoster virus (VZV)-specific immunity in seropositive adults after inhalation of inactivated or live attenuated varicella vaccine [J] . Terada K, Niizuma T, Ogita S, Vaccine . 2002,第31a32期

机译：吸入灭活或减毒水痘减毒活疫苗后，血清阳性成人中水痘带状疱疹病毒（VZV）特异性免疫反应
2. Protocol of a randomised controlled trial characterising the immune responses induced by varicella-zoster virus (VZV) vaccination in healthy Kenyan women: setting the stage for a potential VZV-based HIV vaccine [J] . Sharon Walmsley, KAVI-ICR Team, Salaheddin M Mahmud, BMJ Open . 2017,第9期

机译：表征健康肯尼亚妇女的水痘带状疱疹病毒（VZV）疫苗诱导的免疫应答特征的随机对照试验方案：为潜在的基于VZV的HIV疫苗奠定基础
3. Varicella-Zoster Virus-Specific Cellular Immune Responses to the Live Attenuated Zoster Vaccine in Young and Older Adults [J] . Weinberg Adriana, Canniff Jennifer, Rouphael Nadine, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2017,第2期

机译：VariCella-Zoster病毒特异性细胞免疫应答对年轻和老年人的活病毒疫苗
4. Antiviral Activity of Cisplatin Derivatives of Methotrexate Against Vaccinia Virus, Varicella Zoster Virus (VZV), Reovirus ST3, and Herpes Simplex Virus (HSV-1) [C] . Michael R. Roner, Charles E. Carraher Jr., Salima Dhanji PMSE Symposia . 2005

机译：甲氨蝶呤对痘苗病毒，植物疱疹病毒（VZV），reoVirus ST3和单纯疱疹病毒（HSV-1）的抗病毒活性
5. Engineering a live attenuated vaccine: Mutational analysis of varicella-zoster virus (VZV) glycoproteins,gI andgE, in recombinant VZV strains. [D] . Mallory, Suzanne. 1997

机译：设计减毒活疫苗：重组VZV株中水痘带状疱疹病毒（VZV）糖蛋白，gI和gE的突变分析。
6. Protocol of a randomised controlled trial characterising the immune responses induced by varicella-zoster virus (VZV) vaccination in healthy Kenyan women: setting the stage for a potential VZV-based HIV vaccine [O] . Catia T Perciani, Walter Jaoko, Sharon Walmsley, 2017

机译：表征健康肯尼亚妇女的水痘带状疱疹病毒（VZV）疫苗诱导的免疫应答特征的随机对照试验方案：为潜在的基于VZV的HIV疫苗奠定基础
7. The Effect of Age on the Immunogenicity of the Live Attenuated Zoster Vaccine Is Predicted by Baseline Regulatory T Cells and Varicella-Zoster Virus-Specific T Cell Immunity [O] . Adriana Weinberg, Lei Pang, Michael J. Johnson, 2019

机译：通过基线调节性T细胞和种子果蛋杆菌病毒特异性T细胞免疫预测年龄对活病变疫苗的免疫原性的影响

Live Attenuated Zoster Vaccine Boosts Varicella Zoster Virus (VZV)–Specific Humoral Responses Systemically and at the Cervicovaginal Mucosa of Kenyan VZV-Seropositive Women

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