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Intestinal Atresia: Experience at a Busy Center of North-West India

机译:肠道闭锁:在印度西北部繁忙的中心体验

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摘要

>Objective: To evaluate the presentation, management, complications and outcome of intestinal atresia (IA) managed at our center over a period of 1 year. >Materials and methods: Records of patients of IA admitted in our center from January 2015 to December 2015 were retrospectively analyzed. Demographic data, antenatal history, presenting complaints, location (duodenal, jejunoileal, colonic) of atresia, surgery performed and peri-operative complications were noted. >Results: Total 78 cases of IA were included in the analyses. Mean age and weight at the time of presentation was 5.8 days (range 0-50), and 1.9 kg (range 1.1-3.2), respectively. IA included duodenal atresia [DA (32)], jejuno-ileal atresia [JIA (40)], colonic atresia [CA (3)] and atresia at multiple-location (sites) in 3 cases. Ninety percent of patients underwent surgery within 5 to 20 hours of admission. All cases of DA except one underwent Kimura's diamond shaped duodeno-duodenostomy. One case with perforated duodenal web underwent duodenotomy with excision of web. Seven patients with JIA and CA required primary stoma, while rest were managed by excision of dilated proximal segment and primary anastomosis. Complications included anastomotic leak in 5, proximal perforation in 2, functional obstruction in 7, aspiration pneumonitis in 3, and wound infection in 6 patients. Mean hospital stay for survivors was 11 days. Overall survival was 63%. >Conclusion: Late presentation, overcrowding in intensive care unit, septicemia, functional obstruction and anastomotic leak are the causes of poor outcome in our series. Early diagnosis, some modification in surgical technique, use of total parenteral nutrition and adequate investigations for other congenital anomalies may improve the outcome.
机译:>目的:评估我们中心为期1年的肠道闭锁(IA)的表现,治疗,并发症和结局。 >材料与方法:回顾性分析了我中心2015年1月至2015年12月收治的IA患者的病历。记录人口统计学数据,产前病史,主诉,闭锁的位置(十二指肠,空肠,结肠),手术及围手术期并发症。 >结果:分析共纳入78例IA。报告时的平均年龄和体重分别为5.8天(范围为0-50)和1.9千克(范围为1.1-3.2)。 IA包括十二指肠闭锁[DA(32)],空肠回肠闭锁[JIA(40)],结肠闭锁[CA(3)]和多处(地点)闭锁3例。 90%的患者在入院后5至20小时内接受了手术。除一个病例外,所有的DA病例均接受了木村的菱形十二指肠吻合术。穿孔十二指肠网的一例行腹膜切开术。 JIA和CA的7例患者需要原发造口,其余的则通过切除近端扩张段和原发性吻合术来处理。并发症包括吻合口漏5例,近端穿孔2例,功能性阻塞7例,吸入性肺炎3例和伤口感染6例。幸存者的平均住院时间为11天。总生存率为63%。 >结论:晚期陈述,重症监护病房拥挤,败血病,功能性阻塞和吻合口漏是导致本研究结果不良的原因。早期诊断,对手术技术进行某些修改,使用全胃肠外营养以及对其他先天性异常进行充分的检查可能会改善预后。

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