Arrhythmic risk assessment in genotyped families with arrhythmogenic right ventricular cardiomyopathy

摘要

AimsArrhythmogenic right-ventricular cardiomyopathy (ARVC) is a genetically determined disorder, mostly caused by mutations in genes encoding desmosomal proteins. We evaluated phenotype/genotype characteristics to predict the risk for the first major arrhythmic event in desmosomal-mutation-associated ARVC families.