Resequencing Study Identifies Rare Renin–Angiotensin–Aldosterone System Variants Associated With Blood Pressure Salt-Sensitivity: The GenSalt Study

摘要

BACKGROUNDThe role of rare variants in blood pressure (BP) salt-sensitivity is unknown. We conducted a resequencing study of the renin–angiotensin–aldosterone system (RAAS) to identify rare variants associated with BP salt-sensitivity among participants of the Genetic Epidemiology Network of Salt-Sensitivity (GenSalt) study.