Function and clinical meaningfulness of treatments for mild Alzheimers disease

机译：轻度阿尔茨海默氏病治疗的功能和临床意义

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IntroductionEffectiveness of Alzheimer's disease (AD) treatments is commonly evaluated with coprimary outcomes; cognition with function to ensure clinical meaningfulness of a cognitive effect.

机译：引言阿尔茨海默氏病（AD）治疗的有效性通常与主要疗效一起评估。具有功能的认知功能，以确保认知效果的临床意义。

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期刊名称 Alzheimers Dementia : Diagnosis Assessment Disease Monitoring
作者
Eric Siemers; Karen Chilcott Holdridge; Karen L. Sundell; Hong Liu-Seifert;
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作者单位

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年(卷),期 2016(2),-1
年度 2016
页码 105–112
总页数 8
原文格式 PDF
正文语种
中图分类老年病学;老年卫生;
关键词
Solanezumab Alzheimers disease Clinical relevance Functional rating scales Cognitive rating scales Global rating scales Mild cognitive impairment Clinical meaningfulness;

机译：索拉尼珠单抗;阿尔茨海默氏病;临床相关性;功能等级量表;认知等级量表;整体等级量表;轻度认知障碍;临床意义;
入库时间 2022-08-17 16:29:19

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专利

1. Meta-analysis of double blind randomized controlled clinical trials of acetyl-L-carnitine versus placebo in the treatment of mild cognitive impairment and mild Alzheimer's disease. [J] . Montgomery SA, Thal LJ, Amrein R International clinical psychopharmacology . 2003,第2期

机译：乙酰基左旋肉碱与安慰剂治疗轻度认知障碍和轻度阿尔茨海默氏病的双盲随机对照临床试验的荟萃分析。
2. Clinically meaningful treatment responses after switching to galantamine and with addition of memantine in patients with Alzheimer’s disease receiving donepezil [J] . Osamu Kano, Hirono Ito, Takanori Takazawa, Neuropsychiatric Disease and Treatment . 2013,第2期

机译：在接受多奈哌齐的阿尔茨海默病患者中，改用加兰他敏和美金刚后，具有临床意义的治疗反应
3. The cooperative international neuromuscular research group Duchenne natural history study: Glucocorticoid treatment preserves clinically meaningful functional milestones and reduces rate of disease progression as measured by manual muscle testing and other commonly used clinical trial outcome measures [J] . HenricsonE.K., AbreschR.T., CnaanA., Muscle and Nerve . 2013,第1期

机译：国际合作神经肌肉研究小组Duchenne的自然史研究：糖皮质激素治疗保留了临床上有意义的功能里程碑，并通过手动肌肉测试和其他常用的临床试验结果指标来降低疾病进展的速度
4. Functional Connectivity Analysis on Mild Alzheimer's Disease, Mild Cognitive Impairment and Normal Aging using fNIRS [C] . Tong Boon Tang, Yee Ling Chan Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2018

机译：使用fNIRS对轻度阿尔茨海默氏病，轻度认知障碍和正常衰老进行功能连接分析
5. Investigating a Multimodal Approach to Clinical Diagnosis of Mild Cognitive Impairment and Alzheimer’s Disease [D] . Flannery, Sean M. 2020

机译：调查多模态方法对轻度认知障碍和阿尔茨海默病的临床诊断
6. Clinically meaningful treatment responses after switching to galantamine and with addition of memantine in patients with Alzheimer’s disease receiving donepezil [O] . Osamu Kano, Hirono Ito, Takanori Takazawa, 2013

机译：在接受多奈哌齐的阿尔茨海默氏病患者中改用加兰他敏和美金刚后具有临床意义的治疗反应
7. Function and clinical meaningfulness of treatments for mild Alzheimer's disease [O] . Siemers Eric, Holdridge Karen Chilcott, Sundell Karen L., 2016

机译：轻度阿尔茨海默氏病治疗的功能和临床意义

Function and clinical meaningfulness of treatments for mild Alzheimers disease

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