Fatty Acid Elongase 7 (ELOVL7) Plays a Role in the Synthesis of Long-Chain Unsaturated Fatty Acids in Goat Mammary Epithelial Cells

摘要

Simple SummaryVery-long-chain elongases are required for the synthesis of essential fatty acids in non-ruminants. Whether the fatty acid elongase 7 (ELOVL7) plays a role in ruminants is unclear. We demonstrated, in goat mammary epithelial cells, that ELOVL7 activation resulted in greater concentrations of vaccenic (C18:1n7) and linoleic (C18:2) acid, and lower concentrations of palmitoleic (C16:1n7) and oleic (C18:1n9) acid. Knockdown of ELOVL7 increased the concentration of C18:1n9. The data support a novel role of ELOVL7 in altering long-chain unsaturated fatty acids in goat mammary epithelial cells.